Fractal Broccoli July 19, 2009
Posted by Matt Brown in Weird.Tags: brocolli, fractal, random
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Random, but cool.

What Does It Mean To Be Human July 16, 2009
Posted by Matt Brown in Transhumanism.Tags: Human Enhancement, Transhumanism
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What does it mean to be human? This question has been with us for as long as we as a species can remember. Entire libraries could be filled with all the opinions, rebuttals, debates and ruminations that have cropped up around it. Its answer has confounded our greatest philosophers, eluded our best scientists and even after 10,000 years of recorded history we are still no closer to unraveling it. It is a question I have no intention of trying to answer here.
You’re probably confused now. You’re probably scratching your head and thinking, “What is this, a bait-and-switch? Why did you start this with a question you‘re not going to answer?” The reason I began this essay with it is because it is a question that is at the heart of much of the debate surrounding human enhancement and needs to be addressed, and the reason I do not intended to answer it is because it is a meaningless question. You read that right. It is meaningless, pointless, unimportant.
I am aware of how strange this may sound, but bear with me. Many of the arguments against human enhancement can be boiled down to the idea that there is something special about humanity, something that would be lost should we begin to drastically change ourselves. So what are these unique qualities, these traits that we stand to lose? To answer that we must ask, what is a human? What defines a being as belonging to humanity? It is not our tools. Many animals have been shown to use tools. What about our intelligence? It is impressive in its scope but it is certainly not unique. Self consciousness? Many animals are aware of their own existence. Our capacity for kindness and altruism? Anyone who has owned a pet knows we are not alone in that. Is it simply a combination of all of these, or is that we do all these things better than the rest of the animal kingdom? Ah, now that requires a slightly longer answer. Let us say for the sake of argument that one day we take a dolphin and alter it. Through genetic engineering and biomechanical augmentation we change it so that it’s abilities rival our own. It can speak, it can manipulate tools, it can think like we do with long term memory, abstract thinking and problem solving, it can do all the things we can do. Let us say we do all these things and ask yourself: have we made this dolphin into a human? No. We have made it a smarter dolphin, a handier dolphin, a more eloquent dolphin, but through all of this it remains a dolphin. It does not become a human because it is not our language, our tools, our intelligence or any combination of these or other features that make us human. A human is defined as belonging to the species Homo Sapiens Sapiens, and the only thing that makes us Homo Sapiens is our DNA, our 36 pairs of chromosomes containing all the genes that when expressed and put together give us a human. That’s it.
If we except that our genes are all that make us who we are then I put the question to you: what is so special about being human? Nothing, there is nothing special about being human and therefore there is no special meaning of being human. If being human is not important, then one of the major arguments against transhumanism and human enhancement falls flat on it‘s face. Then we are left with a different question; if being human is not important, than what is. The purpose of this article is not to answer this question but since different people will have different opinions I’ll offer my own here. What is important is not being human but being a person, where a person is defined as a being capable of self-awareness.
Still, there are those who will never except this more humble position for humanity. For many of us our whole view of the world is based around the idea that we are at the center of it, an idea that has survived since ancient times. It used to be that we were at the center of the very universe, put there by the hand of God himself. When that idea fell by the wayside our position changed slightly. If we are not the center of the universe we said at least we are the only possible intelligent life in that universe, living on our unique little life bearing planet. That view was defeated when we saw the sheer size of the universe and found our first extra solar planet. How, in the face of so many worlds around so many stars in so many galaxies, could we possibly believe that we are the only ones. If not that, then at least we are the masters of our own planet we said, the top predator on earth, and for 10,000 years we have been. But that time is coming to an end.
We are approaching a time in the history of our species when the ability to alter ourselves will be in our grasp. In the coming decades we will gain the ability to change our bodies, our minds, our very DNA. We can, if we choose, become something other than human. What will it mean to be post-human. No more than what it means to be human.
Lose Weight by Exhaling Fat July 8, 2009
Posted by Matt Brown in Genetics.Tags: gene therapy, Human Enhancement, weight loss
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No this is not a joke. A study published in Cell Metabolism shows that genetic alterations in mice allowed them to convert fat into carbon dioxide. Let me say that again. Convert fat into carbon dioxide.
When I first read that my jaw dropped and I shouted “what the fuck” probably louder than I should have. Even to a science nut like me who thinks that proper application of technology is the answer to most of the worlds problems and that the singularity is only decades away, this sounds crazy. But on further reading and retrospection it’s actually not too far fetched.
According to the article the researchers injected DNA from bacteria into cultured human cells. In bacteria the DNA coded for enzymes that converted fat into sugar but in the human cells they found the enzymes converted fat into carbon dioxide. They then injected the genes into the livers of lab mice and found the same effect. Fat was converted not into sugar but into CO2, and the mice who had the new genes stayed thin and athletic despite being on a high fat, high calorie diet. Many more tests need to be run to determine if there are any side effects but at first glance it seems safe.
Now I realize this sounds pretty far fetched, but it’s certainly not out of the realm of possibility. Fat is made up of essentialy just three molecules: hydrogen, carbon and oxygen. As a matter of fact, most food is made up of those three molecules plus nitrogen. If two substances are made out of the same stuff, all you really need to do to change one into the other is rearrange the structure of the molecules (think coal and diamonds.) Since the raw material are already in place, the right enzyme could certainly manage to do the trick. Perhaps someday all you’ll need to do to lose weight is take a deep breath.
http://www.hplusmagazine.com/articles/health-medicine/inhale-exhale-diet
Easter Island Compound Shows Anti-aging Properties July 8, 2009
Posted by Matt Brown in Longevity.Tags: anti-aging, Longevity, Transhumanism, rapamycin
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When I first read this I thought it must either be a joke or some new age mumbo-jumbo, but this seems to be for real. Scientists have found that a compound called rapamycin, first found on Easter Island, may have longevity enhancing capabilites. What is more interesting is that it seems to have this effect regardless of what age it is administered. This could be a big step forward because caloric restriction, the only way outside of gene therapy to increase lifespan, doesn’t seem to be effective when implemented in elderly animals. Rapamycin, which is also used in stents and transplant operations, seems to affect the same metabolic pathways as caloric restriction but may be a more effective treament because of this. Another way it may be better than caloric restiriction is that people may actually use it. Anyone can tell you that asking people to cut down their calories for the rest of their lives is a strategy doomed to fail, but asking people to sprinkle a drug on their food for the same effect is a different story.
Americans Still Getting Fatter July 1, 2009
Posted by Matt Brown in Fitness.Tags: Longevity, weight loss
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This is bad news. Obesity rates went up in 23 states last year. Many of those are baby boomers that are starting to hit retirement age. That health care overhaul better come fast.
Mediterranean Diet Improves Longevity, But Some Foods More Important Than Others June 23, 2009
Posted by Matt Brown in Longevity, Nutrition.Tags: anti-aging, Longevity, Nutrition
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It seems the much touted Mediterranean Diet is a bit more nuanced than we may have thought. A recent study found that certain foods commonly found in the diet are more important than others. Specifically eating more vegetables, fruits, nuts, pulses and olive oil, and drinking moderate amounts of alcohol was linked to greater longevity while eating more fish, seafood and cereal was not. Read the whole article in the link below.
New Technique Kills Cancer By Cutting Off It’s Food June 15, 2009
Posted by Matt Brown in Genetics, Longevity.Tags: cancer, gene therapy, Longevity
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Cancer is the number one killer in the United States, is responsible for 13% of all human deaths, and even for those it doesn’t kill it leads to a drastic decrease in quality of life. As such, any serious discussion about improving human longevity has to start with treating and curing cancer. Thankfully scientist don’t need us to remind them of that and have been hard at work looking for better and better ways to stop this deadly disease. One such group is a team at the University of Florida, who have developed a new gene therapy which treats cancer by cutting of the supply of blood to the tumor.
To do this, the researchers developed what they call a “fusion protein” which was delivered into the cells by a transposon they call Sleeping Beauty. The imbedded protein does two things: first, it promotes thrombosis, or blood clotting, and second it reduces blood vessel density inside the tumor. Both of these effects result in the tumor receiving less nutrients. The researchers found that in their test mice tumor volume decreased 53 percent and cancer cell growth slowed by 49 percent.
S.O.D, Antioxidant Which Could Slow Aging Process June 11, 2009
Posted by Matt Brown in Longevity.Tags: anti-aging, antioxidant, Longevity
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Here’s an interesting article about an enzyme that may be an important factor in the fight against aging. Superoxide dismutase (S.O.D, a rather amusing acronym) is an important antioxidant that is produced in the body and helps eliminate the dangerous free radicals that we all hear so much about.
For those of you who don’t know free radicals are basically ions (oxygen ions being the most commonly talked about) that have lost an electron, usually during aerobic glycolisis when oxygen is used to produce energy. Since they lack an electron these free radicals roam around the body searching for cells to steal one from. In doing so they damage whatever part of the cell they took it from which can be very dangerous if they happen to take one from your DNA, damaged DNA being the main cause of cancer. Antioxidants are important because they neutralize the free radicals by sharing one of their electrons, thus removing the danger.
S.O.D. is important for a few reasons. One, it is an antioxidant which as we’ve already established is something you want in your body. Two, it is produced by the body rather than being taken in from food. According to the article ”[internally produced] enzymes are vastly more potent than dietary antioxidants, such as vitamin C. S.O.D., for example, is 3,500 times more potent than vitamin C at reducing superoxide radical.” Three, there seems to be some evidence that the amount of S.O.D your body produces is correlated with longevity. Animals with large amount of S.O.D have longer lifespans than those with smaller amounts.
Unfortunately like most things in your body the production of S.O.D decreases with age. As such researchers are attempting to find a way to keep levels of the antioxidant at youthful levels. The article lists a few scientists who are working on a solution, though there products seem to fall under the category of promising, but not quite there yet.
http://www.hplusmagazine.com/articles/forever-young/longevity
Improving IQ by Improving the Brain’s Wiring June 10, 2009
Posted by Matt Brown in Human Enhancement, Transhumanism.Tags: Human Enhancement, intelligence
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Don’t get your hopes up, they haven’t invented a a smart pill for us yet. Scientists at Utrecht University Medical Center have found that how efficiently your brain is wired may account for a large part of you intelligence. Researchers studied the brains of subjects at rest using MRI and found that connectivity accounted for 30% of the difference between subjects studied, though interestingly enough researchers did not find a link between the total number of connections in the brain and IQ. All this sounds pretty interesting but allow me to rain on your parade by pointing out that the study only contained 19 subjects. Not to say the findings are false but I’d like to see a larger study. Read the full story in the link below.
New “Tomato Pill” Reduces Risk of Heart Disease June 6, 2009
Posted by Matt Brown in Nutrition.Tags: antioxidant, Longevity, lycopene, Nutrition
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I’m glad I eat tomatos. Ateronon is a new supplement that’s being marketed as a way to stave off heart disease and stroke. The pill contains a phytochemical called lycopene, which is commonly found in tomato skins where it is responsible for the red color. What lycopene seems to do is reduce the oxidation of harmful fats in the blood. While for most of us a diet high in fruits and vegetables is probably enough this sounds like a promising supplement for those with a high risk of heart disease.